Higher Vitamin D Levels May Lower Breast Cancer Risk

Higher levels of vitamin D may be protective against breast cancer, a study in PLOS ONE suggests. Researchers examined the relationship between 25-hydroxyvitamin D (25[OH]D concentration and breast cancer risk across a broad range of 25(OH)D concentrations (<20 to ≥60 ng/mL) among women aged 55 years and older participating in three previous studies (pooled cohort, 5,038 participants). The researchers found there was an 82% lower incidence rate of breast cancer for women with 25(OH)D concentrations ≥60 versus <20 ng/mL.

Fri, 13 Jul 2018 BREAKING NEWS
Blacks Have Elevated HTN Risk Through Age 55 Years

Blacks have considerably increased risk for hypertension than whites through age 55 years, regardless of blood pressure levels through young adulthood, research in the Journal of the American Heart Association suggests. The researchers found in black men, black women, white men, and white women, the cumulative incidence of hypertension by age 55 years was 75.5, 75.7, 54.5, and 40.0 percent, respectively. Among blacks and whites, a higher Dietary Approaches to Stop Hypertension diet adherence score correlated with lower risk.

Fri, 13 Jul 2018 BREAKING NEWS
Basal Insulin Analogs Don’t Cut Hypoglycemia-Linked ER Visits

Initiation of a basal insulin analog versus human neutral protamine Hagedorn (NPH) insulin isn't associated with reduction in risk of hypoglycemia-related emergency department (ED) visits or hospital admissions, research in Journal of the American Medical Association suggests. Researchers found there were 39 hypoglycemia-related ED visits or hospital admissions among 1,928 patients who initiated insulin analogs, compared with 354 hypoglycemia-related ED visits or hospital admissions among 23,561 patients who initiated NPH insulin during a mean follow-up of 1.7 years.

Fri, 13 Jul 2018 BREAKING NEWS
Metformin Tied to Acidosis Risk at eGFR

Metformin use is associated with an increased risk of acidosis at estimated glomerular filtration rate (eGFR) <30mL/min/1.73 m², research in JAMA Internal Medicine finds. Researchers quantified the correlation between metformin use and hospitalization with acidosis among 75,413 patients with diabetes. The results were replicated in 67,578 new metformin users and 14,439 new sulfonylurea users from 2010 to 2015. "Our results support cautious use of metformin in patients with type 2 diabetes," the authors write.

Thu, 12 Jul 2018 BREAKING NEWS
CDC: Nearly One-Third of Injury Deaths Occur at Home

Just under one-third of deaths from all causes of injury occur in the person’s home, according to a QuickStats report published in the CDC’s Morbidity and Mortality Weekly Report. In 2016, the total number of deaths by all injury types was 231,991. “More than half of the deaths attributable to poisoning (52%) occurred in the home,” the authors write. “Approximately 44% of deaths from firearms and suffocation occurred in the home.”

Wed, 11 Jul 2018 BREAKING NEWS
Attending Surgeon Influences Genetic Testing in Breast Cancer

The attending surgeon is associated with variation in the receipt of genetic testing after breast cancer diagnosis, according to research in JAMA Surgery. The researchers found that 34.5% of patients had an elevated risk of mutation carriage and 27.0% underwent genetic testing. There was a more than two-fold increase in the odds of a patient receiving genetic testing if she saw a surgeon with an approach one standard deviation above that of a surgeon with the mean test rate.

Wed, 11 Jul 2018 BREAKING NEWS